Head & Neck · Organ at risk

Lips

Educational Summary

Dose constraints

Head & Neck Planning Essentials

ScheduleConstraintSource
Conventional fractionation
70 Gy / 35 fx definitive · 60–66 Gy / 30–33 fx post-op
Mean <20 GyRTOG 0920
Max <30 Gy (non-oral cavity), <50 Gy (oral cavity)RTOG 0920

Quoted from RTOG 0920, checked 2026-09-24. Full table with references →

Anatomy

The upper and lower lips, in front of the oral cavity.

Function in the body

The lips close the mouth, keep food and saliva in, and help with speech and facial expression.

Why it matters

The lips are contoured apart from the oral cavity because the goal is to keep them much lower — lip mucositis and cracking are painful and visible. They are easiest to spare when the target is posterior, as in larynx cancer, and hardest in anterior oral cavity cancer.

How to contour

Brouwer 2015 runs the lip contour from the lower edge of the nose to the top of the mandibular body, and includes the inner surface of the lips (Table 1):

  • Top: the hard palate (at the sides) and the anterior nasal spine (in the midline).
  • Bottom: the lower edge of the tooth sockets and the top edge of the mandibular body.
  • Front: the outer surface of the skin.
  • Back: the mandibular body, teeth, tongue, and air if present.
  • Sides: the depressor anguli oris, buccinator, and levator anguli oris/risorius muscles.

The mucosa in front of the jaws belongs to the lips; the mucosa to the side belongs to the buccal mucosa. RTOG 0920 asks for the lips and oral cavity as two separate structures.

Further reading

  • RTOG 0920 — RTOG 0920 protocol — A Phase III Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab for Locally-Advanced Resected Head and Neck Cancer Source

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