Consensus CT delineation guidelines for head and neck organs at risk from eight cooperative groups, with anatomical descriptions and example images. Citation checked against Crossref; content not yet reviewed by DoseLab.
Head & Neck · Organ at risk
Submandibular Glands
Dose constraints
Head & Neck Planning Essentials
| Schedule | Constraint | Source |
|---|---|---|
| Conventional fractionation 70 Gy / 35 fx definitive · 60–66 Gy / 30–33 fx post-op | Mean ≤39 Gy | Murdoch-Kinch 2008 |
Quoted from eviQ 5049, checked 2026-09-24. Full table with references →
Anatomy
Salivary glands beneath the floor of the mouth, in the submandibular triangle along the inner surface of the mandible — within neck level Ib.
Function in the body
Salivary glands under the floor of the mouth. They produce much of the saliva that keeps the mouth moist between meals.
Why it matters
The submandibular glands produce most of the resting (unstimulated) saliva that keeps the mouth moist between meals and overnight. They can be spared only when level Ib is not in the target, which depends on the subsite and nodal stage.
How to contour
Brouwer 2015 gives these boundaries (Table 1):
- Top: the medial pterygoid and mylohyoid muscles.
- Bottom: fatty tissue.
- Front: the outer surface of the mylohyoid and hyoglossus muscles.
- Back: the parapharyngeal space and the sternocleidomastoid muscle.
- Outside: the inner surfaces of the medial pterygoid muscle and the mandible, and the platysma.
- Inside: the outer surfaces of the mylohyoid and hyoglossus muscles, the superior and middle pharyngeal constrictors, and the anterior belly of the digastric muscle.
Consensus guidelineUnder Review
CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines
Brouwer CL, Steenbakkers RJ, Bourhis J, et al. · 2015
Further reading
- Murdoch-Kinch 2008 — Dose-effect relationships for the submandibular salivary glands and implications for their sparing by intensity modulated radiotherapy Source